Offer Salivary Testing as Part of Standard Care Through DentuluPro

Identify hidden pathogens, assess genetic inflammation risk, and screen for HPV-related oral cancers all from a simple chairside saliva rinse. DentuluPro gives your practice the infrastructure to integrate salivary diagnostics into everyday workflows.

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Salivary Testing
Why Salivary Diagnostics

Belong in Every Practice

Your clinical exam reveals what’s visible. Salivary diagnostics reveal what’s hidden the specific bacteria driving disease, genetic inflammation markers, and early viral risks that X-rays and probing alone cannot detect. Platforms like OralDNA have pioneered DNA based pathogen testing in dentistry, while Viome® has expanded microbiome intelligence using RNA-based analysis and AI modelling. For the first time, dental providers can make treatment decisions based on molecular-level data not just clinical observation.

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47%

Adults have periodontal disease

many undiagnosed

225%

Increase in HPV cancers

over past two decades

90%

Oral-Systemic Manifestations

saliva can help identify
Specific bacterial strains driving periodontal destruction
Genetic predisposition to exaggerated inflammatory response
Subclinical HPV infections before lesions appear
Cariogenic bacterial load causing recurring cavities

Diagnostic Report

MyPerioPath® Result
HIGH RISK DETECTED
1.2 × 108
4.8 × 107
2.1 × 107

Clinical Guidance

"High concentrations of High-Risk pathogens detected. Recommend systemic antibiotic therapy (Amoxicillin + Metronidazole) alongside SRP."
View Sample Report
Diagnostic Tests

You Can Offer

All tests use a simple, non-invasive saliva rinse collection performed chairside. Results are delivered through a secure HIPAA-compliant online portal in 7–10 business days with actionable clinical guidance. Choose between OralDNA’s targeted oral pathogen analysis or Viome’s full-body health intelligence testing.

OralDNA® Model

With salivary PCR-based diagnostics, providers can identify specific pathogens and customize clinical protocols.

Identify specific periodontal pathogens
Stratify disease severity
Customize antibiotic protocols
Monitor post-SRP effectiveness
Reduce refractory perio cases

Objective microbial data improves patient education and case acceptance.

Explore Oral DNA® Test
Viome® Model

Advanced microbiome analysis enables personalized preventive programs and host-microbiome interaction insights.

Personalized preventive programs
Inflammatory risk assessment
Nutritional correlations
Host-microbiome interaction insights
Valuable for airway-focused practices

This is particularly valuable for integrative and airway-focused practices.

Explore Viome® Testing

DentuluPro handles the logistics.

You focus on the clinical decisions

DentuluPro seamlessly coordinates the entire sleep apnea journey from chairside collection to lab analysis and monitoring bringing providers and technology together in one connected workflow.

Start Offering Salivary Diagnostics
01
Enroll as a Provider

Sign up through DentuluPro at no cost. Get live training for your team and access to the OralDNA® portal instantly.

02
Chairside Collection

A simple 30-second saline rinse collection. No fasting or prep required. Takes less than 5 minutes of chair time.

03
Ship to Lab

Prepaid FedEx shipping labels generated automatically. Track every sample from your office to the OralDNA® lab.

04
Expert Lab Analysis

OralDNA® Labs performs PCR DNA sequencing to identify specific pathogen loads and genetic risk markers.

05
Actionable Reports

Results in 7-10 days via secure portal. Personalized reports provide specific antibiotic and treatment guidance.

Grow Your Practice with

Preventive Diagnostics

Salivary testing isn’t just better clinical care it’s a sustainable growth strategy. Practices that integrate salivary diagnostics see measurable improvements in case acceptance, patient retention, and per-patient revenue.

Start Offering Salivary Diagnostics
Increase Case Acceptance

Patients are more likely to accept treatment with objective lab data. A report showing specific bacteria changes “you should consider this” to “here’s what’s happening.”

Improve Patient Retention

MyPerioProgress® testing encourages patients to return every 6–12 months. Monitoring pathogen levels proves treatment works.

Increase Case Acceptance

Salivary testing offers a billable diagnostic service without new equipment or extensive training. Many insurance plans cover it for chronic conditions.

Differentiate Your Practice

Position your practice as a leader in preventive dentistry. Salivary diagnostics show patients your evidence-based approach to care.

The Mouth-Body
Systemic Map

Salivary diagnostics reveal how specific oral pathogens impact systemic health. By mapping the mouth-body connection, you move beyond “cleanings” to preventative systemic healthcare.

01
Cardiovascular Disease

Periodontal pathogens are in plaques. Chronic inflammation adds to systemic issues.

04
Rheumatoid Arthritis

P. gingivalis linked to autoimmune pathways worsening joint disease.

02
Diabetes

Diabetes worsens periodontal disease, and vice versa.

05
Oral & Oropharyngeal Cancer

HPV types 16 and 18 cause many oral cancers. Salivary screening detects risk early.

03
Adverse Pregnancy Outcomes

Oral pathogens linked to preterm birth. Testing enables early intervention.

06
Alzheimer’s & Cognitive Decline

Research links P. gingivalis and oral infection to cognitive decline.

Systemic Map

Salivary diagnostics that
drive impact

Salivary diagnostics don’t exist in isolation. Through DentuluPro, they connect to every part of how you educate patients, coordinate care, and grow your practice. We combine strategy, clinical data, and visual clarity to transform raw results into actionable patient outcomes.

Explore Ecosystem
Diagnostic App

Inside the Ecosystem

Here's how salivary diagnostics integrate with our core services:

AI Dental Assistant

Educate patients about salivary testing before they even arrive.

My Dental Chart

Integrate salivary test results into the patient's comprehensive oral health record.

Professional Copilot

AI-assisted clinical decision support helps you interpret results and plan care.

Sleep Apnea Screening

Combine salivary diagnostics with airway screening for comprehensive care.

DentuluPro Pay

Offer flexible payment options for testing services.

Sell on DentuluPro

Offer test kits and related products through your storefront.

Billing, Coding & Compliance

DentuluPro provides coding guidance and billing support to help you maximize reimbursement.

CDT Codes for Salivary Diagnostics
Code Description
D0417 Collection and preparation of saliva sample for laboratory diagnostic testing
D0418 Analysis of saliva sample chemical or biological analysis for diagnostic purposes
Insurance

Many plans cover testing for systemic conditions.

Compliance

CLIA & CAP Accredited, FDA-Cleared Devices, HIPAA Compliant.

Evidence-Based

Supported by over 50 peer-reviewed studies.

Integration Touches Everything. Here’s How It Connects.

Caries Risk Assessment AI Powered Diagnostics OralDNA® Salivary Diagnostics Viome testing Salivary Testing kits
Ecosystem Overview
Oral Appliances Sensitivity and Caries Prevention Dental Office App Implementation Dentulu Pro home page Ecosystem Overview

Provider FAQ

Find answers to common questions about clinical implementation, billing, and regulatory requirements for dental sleep medicine.

Still have questions?

Our clinical specialists are ready to help you navigate the transition to offering sleep services.

Contact Support @ (888)-905-0226

There is no cost to enroll as a provider. DentuluPro handles onboarding, and OralDNA® provides a dedicated Clinical Specialist for live training webinars at no charge. You only pay for test kits as you order them.

No special equipment is required. Collection uses a simple saline rinse kit. Your hygienist or dental assistant can perform the entire collection in under 5 minutes. OralDNA® provides personalized live webinar training for your team.

DentuluPro provides patient education materials and scripting guidance. The AI Dental Assistant on your website can pre-educate patients before they visit. Most patients respond positively when presented with objective lab data that explains their condition in clear, personal terms.

Yes. The collection process a 30-second saline rinse falls within the scope of practice for dental hygienists and dental assistants in most states. Check your state’s regulations for specifics.

Results are delivered in 7–10 business days through the secure OralDNA® online portal. Reports include pathogen identification, risk scoring, and clinical recommendations.

Many medical insurance plans cover testing when linked to systemic or chronic conditions. Dental billing uses CDT codes D0417 (collection) and D0418 (analysis). DentuluPro provides coding guidance to help maximize reimbursement.

For active infections: every 6–8 weeks after treatment to confirm pathogen reduction. For ongoing monitoring: every 6–12 months depending on risk factors. Follow-up tests generate MyPerioProgress® reports that track bacterial changes over time.

No. Salivary diagnostics complement never replace your clinical examination. They provide molecular-level data that visual examination and probing cannot detect, giving you a more complete picture for treatment planning.